维生素D缺乏是否会导致过敏性肠道炎的发生?
Ozlem Akbulut1, Burcu Tahire Köksal2, Beril Aydın1
1Department of Pediatrics, Medical Faculty, Baskent University, Ankara, Turkey.
患有过敏性长肠炎 (AP) 的婴儿的维生素D水平较低. 低维生素D与发展AP的风险更高有关,这表明潜在的关联和需要评估.
科学领域:
- 儿科过敏和免疫学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 全球上升的过敏性疾病的流行率,包括过敏性乳头炎 (AP),在婴儿.
- 提高对维生素D (维生素D) 缺乏及其在免疫介导疾病中的潜在作用的认识.
研究的目的:
- 为了评估被诊断患有过敏性肠道炎 (AP) 的婴儿的维生素D (维生素D) 水平.
- 探索维生素D状况与婴儿AP发展之间的潜在关系.
主要方法:
- 展望性,观察性,病例控制研究设计.
- 包括6个月及以下的婴儿:有72名AP和44名健康对照.
- 在AP患者和对照者之间诊断时血清维生素D水平的比较.
主要成果:
- 与健康对照人群相比,在患有AP的婴儿中观察到显著较低的维生素D水平.
- 维生素D缺乏或不足在34.7%的婴儿中被发现.
- 维生素D水平低于40.75毫克克/升的婴儿患AP的风险高3.5倍.
结论:
- 患有AP的婴儿的维生素D水平较低,支持维生素D缺乏与该疾病之间的关联.
- 调查结果可以提供有关环境因素的见解,这些因素有助于AP的日益流行.
- 建议对被诊断为AP的婴儿进行维生素D水平的例行评估.
更多相关视频
09:04DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
06:57Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
Published on: September 18, 2016
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
