在患有类风湿性部狭窄症的患者中,静音脑梗塞
Imane Najmi1, Adil Ouafi2, Ismail Oughebbi3
1Neurology department (I.N, M.F.B), Hassan II University Hospital, Fez, Morocco; Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdallah University, Fez, Morocco.
Clinical neurology and neurosurgery
|December 31, 2024
概括
沉默性脑梗塞 (SBI) 在风湿性心肌狭窄症 (MS) 患者中很常见,随着年龄和MS严重程度的增加而增加. 左心房扩大 (LA) 是一个关键预测因素,即使没有心房动 (AF).
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 沉默性脑梗塞 (SBI) 经常在脑成像研究中观察到.
- SBI和类风湿性关节狭窄症 (MS) 之间的联系需要进一步调查.
- 这项研究探讨了使用MRI的风湿性MS患者SBI患病率.
研究的目的:
- 确定SBI在神经学上无症状的类风湿性MS患者中的患病率.
- 在这个人群中确定与SBI发生相关的心脏异常.
主要方法:
- 摩洛哥费斯的一项双中心,横截面研究包括100名神经学上无症状的风湿性MS患者.
- 大脑MRI被用来检测SBI. 胸外心声扫描评估了额头膜区域和左心房 (LA) 大小.
- 单变量和多变量分析检查了SBI和临床/心声学变量之间的关联.
主要成果:
- 56%的患者 (56/100) 患有SBI,其中7人表现出缺口模式.
- 如果SBI患者服用口服抗凝剂 (OAC),他们年龄较大,MS更严重,INR控制较差.
- 扩大LA与SBI有很强的关联,无论心脏节奏 (心房动或鼻节奏).
结论:
- 风湿性MS患者面临SBI的高风险.
- 风险因素包括晚年,MS严重程度,特别是左心房 (LA) 扩大,即使没有心房动 (AF).
- 扩大LA和不稳定INR是MS患者SBI的独立预测因素.
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