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Updated: Jun 4, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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在黑色素瘤中,TPC2控制着MITF的表达和转移

M Raza Zaidi1, Jonathan Soboloff1

  • 1Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA; Department of Cancer & Cellular Biology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.

Cell calcium
|December 31, 2024
PubMed
概括

黑色素瘤的进展依赖于双孔通道2 (TPC2) 和Rab7a,由MITF基因调节. Wnt信号调解了这一点,影响了癌细胞的生长和扩散.

关键词:
lysosome 是一个溶解体.美国MITF MITF黑色素瘤是一种黑色素瘤.在TPC中,TPC是TPC.他们不想做.

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