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评估肺癌放射治疗症状的专业患者差异:一项国际多中心研究

Miguel E Aguado-Barrera¹, Carlos Lopez-Pleguezuelos¹, Antonio Gómez-Caamaño²

¹Grupo Genética en Cáncer y Enfermedades Raras, Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain; Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain.

Lung cancer (Amsterdam, Netherlands)

|December 31, 2024

概括

医疗保健专业人员和肺癌患者在很大程度上同意可观察到的治疗副作用. 然而,像呼吸障碍这样的主观症状的持续性较小,受疲劳和先前化疗等因素的影响.

科学领域:

在瘤学瘤学.
患者报告的结果
临床试验临床试验

背景情况:

肺癌治疗可能会引起各种症状,影响患者的幸福感.
患者报告和临床医生评估的与治疗有关的症状之间存在差异.
了解这些差异对于有效的症状管理至关重要.

研究的目的:

调查肺癌患者和医疗保健专业人员之间评估治疗相关症状的差异.
确定影响这些评估差异的因素.

主要方法:

分析了REQUITE研究中515名参与者的数据.
评估五个关键症状 (咳,呼吸不全,支气管肺出血,胸壁疼痛,消化不良) 放射治疗前后.
使用Gwet的AC2系数和分层分析量化协议.

主要成果:

在支气管肺出血和消化不良方面观察到高一致性.
咳和胸壁疼痛的实质性协议;呼吸障碍的最低协议.
之前的化疗,慢性肺炎和癌症早期阶段影响呼吸不良的评估协议.
疲劳在多种症状评估中显著减少了一致性.

结论:

对于可观察到的症状存在强烈的对齐,但像呼吸障碍这样的主观症状的一致性较小.
临床因素 (化疗,COPD,阶段) 和生活质量 (疲劳) 影响症状评估.
整合生活质量数据对于准确的症状感知和管理至关重要.

关键词:

相关性指标是指相关性指标.疲劳疲劳疲劳疲劳疲劳肺癌是一种肺癌.患者报告的结果衡量患者报告的结果.生活质量生活的质量.辐射的影响辐射影响症状评估症状评估症状评估

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