药房综合过渡 (PIT) 试验:实用集群随机交叉试验的协议
Mariam N Hantouli1, Sarah E Monsell2, Giana H Davidson3
1University of Washington Department of Surgery, Seattle, Washington, USA hantouli@uw.edu.
药房综合过渡 (PIT) 计划改善了医院到熟练护理机构过渡期间的药物安全. 这种干预减少了药物错误,并提高了患者护理协调.
科学领域:
- 提供医疗保健的科学.
- 患者安全研究的研究.
- 药物管理系统是药物管理系统.
背景情况:
- 医院到熟练护理机构 (SNF) 的过渡是复杂的,导致重大成本和不良事件.
- 药物错误在护理过渡期间影响大约70%的患者,导致痛苦和再入院.
- 现有的协议往往无法确保有效的药物管理和医院和SNF团队之间的沟通.
研究的目的:
- 评估药房综合过渡 (PIT) 计划在改善患者护理过渡方面的有效性.
- 为了比较PIT计划对药物安全和沟通的影响与常规护理.
- 描述利益相关者对PIT项目的实施,有效性和可持续性的看法.
主要方法:
- 一个平行集群随机控制交叉试验设计,涉及华盛顿州的4家医院和14家SNF.
- 根据患者数量分层的SNF被随机分配到PIT计划或通常的护理中.
- 主要结局是出院后30天内与药物相关的问题,次要结局包括不良事件和再入院. 混合方法评估评估了利益相关者的观点.
主要成果:
- PIT试验正在进行中;初级和二级结局数据尚未提供.
- 正在收集利益相关方关于实施忠实性,有效性和支持需求的观点.
- 研究设计允许对PIT计划对护理过渡的影响进行严格的评估.
结论:
- 药房综合过渡 (PIT) 计划有可能在护理过渡期间提高药物安全和沟通.
- 预计进一步的结果将为管理从医院转移到SNF的患者提供最佳实践信息.
- 该研究将为旨在改善医疗保健转型的干预措施的实施和维持提供有价值的见解.
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