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染色体层次的基因组组合和Barbel chub Squaliobarbus curriculus的注释

Qingmei Zheng¹, Feng Huang¹, Haiyan Zheng²

¹Guangdong Provincial Key Laboratory of Conservation and Precision Utilization of Characteristic Agricultural Resources in Mountainous Area, School of Life Sciences, Jiaying University, Meizhou, 514015, China.

Scientific data

|December 31, 2024

概括

创建了一个染色体层次的基因组组合,用于barbel chub (Squaliobarbus curriculus). 这种资源支持水产养殖和这种经济重要淡水鱼的遗传育种.

科学领域:

水产养殖是水产养殖的一种方式.
基因组学就是基因组学.
鱼类学鱼类学鱼类学

背景情况:

鱼 (Squaliobarbus curriculus) 是中国的一个重要的淡水鱼.
野生种群的减少需要水产养殖的发展.
缺少高质量的基因组组件用于人工和遗传育种.

研究的目的:

为了生成Squaliobarbus curriculus的染色体级基因组组合.
为物种的保护和繁殖计划提供必要的基因组资源.

主要方法:

使用了HiFi测序,Hi-C测序,Iso-seq和短读RNA-seq数据的组合.
构建了一个910.27 Mb的基因组组件,具有34.70 Mb的N50结合.
使用Hi-C数据将99.50%的序列定在24个染色体上.

主要成果:

确定了28,329个编码蛋白质的基因,其中96.04%的功能注释.
标注了各种非编码RNA,包括2041个小RNA,16426个tRNA,5488个rRNA和1536个snRNA.
实现了高度连续的染色体水平组合.

结论:

在Squaliobarbus curriculus的染色体水平基因组组合是一个显著的进步.
这种基因组资源将促进遗传育种,种群基因组学和标记物识别.
它对于可持续的水产养殖和物种保护至关重要.

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