相关实验视频

Updated: May 7, 2025

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

检查初始血清乳酸水平升高与创伤患者的死亡率和发病率的关联:一项回顾性研究

Pablo Rodríguez-Ortiz^1,2, Kyara Berríos-Toledo^3,4, Ediel O Ramos-Meléndez^1,2

¹Trauma Research Program, School of Medicine, Department of Surgery, University of Puerto Rico, Medical Sciences Campus, P.O. Box 365067, San Juan, 00967, Puerto Rico.

International journal of emergency medicine

|December 31, 2024

概括

在创伤患者中初始血清乳酸 (iSL) 水平升高并不能独立预测死亡率或重症监护室 (ICU) 的入院. 然而,iSL是一种快速可用的标记物,可以帮助临床决策.

科学领域:

创伤护理创伤护理
临床化学临床化学
临界护理医学临界护理医学

背景情况:

最初的血清乳酸盐 (iSL) 用于评估创伤严重程度,但其对死亡率和发病率的预测准确性不一致.
这项研究调查了iSL与波多黎各创伤医院 (PRTH) 患者结果之间的关联.

研究的目的:

评估初始血清乳酸盐 (iSL) 水平升高对创伤患者死亡率和发病率的预测值.
确定iSL是否可以独立预测诸如住院死亡率,创伤重症监护室 (TICU) 住院和机械通风 (MV) 需求等结果.

主要方法:

在2014年7月至2019年6月期间接受PRTH治疗的18岁或以上的536名创伤患者的回顾性研究.
患者根据iSL水平 (正常与升高) 进行了分类. 统计分析包括t测试,威尔科克森等级和测试,奇平方测试,费舍尔的精确测试,回归和ROC分析.

主要成果:

升高的iSL最初与更高的住院死亡率,TICU入院和需要MV相关.
然而,经过调整后的分析显示,ISL升高与这些结果之间没有显著的独立关联.
无论是iSL还是伤害严重性得分 (ISS),都显示出死亡率的预测能力有限,两者之间没有显著差异. 患有升高iSL的患者在医院和TICU停留时间更长,并受到严重伤害.

结论:

在创伤患者中,升高的iSL水平可能不是死亡率,TICU入院或MV要求的独立预测指标.
尽管如此,iSL的快速可用性支持其作为创伤护理决策中的补充标记物的使用.
使用iSL与其他临床指标一起,可能会改善创伤患者的治疗结果.

关键词:

住院死亡率住院死亡率最初的血清乳酸水平.重症监护室的重症监护室是重症监护室的重症监护室.机械通风机械通风机械通风机创伤患者患者的创伤患者.

更多相关视频

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

The Effect of Anti-Fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model

The Effect of Anti-Fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model

Published on: April 12, 2024

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

Muscle Recovery and Fatigue

Muscle Recovery and Fatigue

Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...