艾滋病毒患者皮肤内镜胃口术 (PEG) 的结果
Nikhitha Mantri1, Haozhe Sun1, Sameer Datta Kandhi2
1Division of Gastroenterology, Department of Medicine, BronxCare Health System, Clinical Affiliate of Mt Sinai Health Systems and Academic Affiliate of Icahn School of Medicine, 10C, 1650 Selwyn Avenue, Bronx, NY, 10457, USA.
BMC gastroenterology
|December 31, 2024
概括
与非HIV患者相比,接受皮肤内镜胃口管 (PEG) 插管的HIV患者面临更高的出血风险和显著增加的一年死亡率. 这凸显了对这一群体的专业护理策略的需要.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 穿皮内镜胃口 (PEG) 管对于无法维持口服摄入的患者的肠道营养至关重要.
- PEG管的放置与包括出血和感染在内的并发症有关.
- 艾滋病毒状况对PEG管结局的影响,特别是死亡率,仍未得到充分研究.
研究的目的:
- 调查艾滋病毒阳性状态对PEG插入后并发症和死亡率的影响.
- 为了比较HIV阳性和HIV阴性患者队列之间的PEG管结局.
主要方法:
- 一个回顾性审查639个PEG管放置在461名患者.
- 85名艾滋病毒阳性患者和艾滋病毒阴性患者之间的并发症和死亡率的比较.
主要成果:
- 艾滋病毒阳性患者在PEG插入部位后出现显著更高的出血率 (15.3%与4.5%,p=0.001).
- 尽管实验室值和药物使用相似,但艾滋病毒组的出血风险较高.
- 与非艾滋病毒组 (17.8%,p<0.001) 相比,艾滋病毒组的1年死亡率 (37.6%) 明显高于非艾滋病毒组 (17.8%,p<0.001).
结论:
- 艾滋病毒状况与PEG管安置后增加的出血并发症和显著更高的1年死亡率有关.
- 提高警和量身定制的管理对于接受PEG手术的HIV患者至关重要.
- 需要进一步的研究来确定潜在的因素,并制定针对性的干预措施,以优化这群人群的护理.
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