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Updated: Apr 28, 2026

Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques
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微质和免疫细胞在多发性硬化症认知障碍中的相互作用:一项死后研究.

Catarina Barros1, Ainhoa Alberro2, Adelaide Fernandes3,4

  • 1Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisboa, Portugal.

Journal of neuroinflammation
|December 31, 2024
PubMed
概括

多发性硬化症 (MS) 的认知障碍与微质过度吞突触有关,特别是那些被标记为C1q的抑制突触. 这一过程可能是由CD8+ T细胞驱动的,突出显示了免疫细胞在MS认知缺陷中的作用.

关键词:
CD8 T 细胞 CD8 T 细胞认知障碍 认知障碍是一种认知障碍.微质细胞中的微质细胞多发性硬化症是多发性硬化症.突触切割是指突触的切割.

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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