富含青叶植物的饮食可以帮助控制Helicobacter pylori感染吗? 一个系统的审查
Sara Properzi1, Fabrizio Stracci1, Margherita Rosi1
1Department of Medicine and Surgery, University of Perugia, Perugia, Umbria, Italy.
Frontiers in medicine
|January 1, 2025
概括
富含布拉西卡植物的饮食显示出,它可以作为Helicobacter pylori (Hp) 感染的辅助疗法,有可能减少炎症并帮助抗生素治疗. 然而,完全消除和减轻抗生素副作用仍然是一个挑战,需要进一步的研究.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 杆菌 (Hp) 感染是一个全球性健康问题,与胃炎,和胃癌有关.
- 抗生素耐药性和副作用限制了当前的HP根除策略.
- 棕植物衍生化合物正在成为HP感染的潜在辅助疗法.
研究的目的:
- 系统地审查布拉西卡ceae丰富的饮食对Helicobacter pylori (Hp) 感染控制的影响.
- 为了评估Brassicaceae与标准抗生素治疗的协同效应.
- 评估Brassicaceae在缓解HP引起的炎症和抗生素副作用方面的潜力.
主要方法:
- 按照PRISMA指南进行系统的文献审查.
- 在MEDLINE PubMed,科学网和科克兰图书馆进行的搜索.
- 包括HP感染人群/细胞培养和Brassicaceae干预的研究;不包括动物研究和无关评论.
主要成果:
- 消费Brassicaceae可能会减少Hp的殖民,但完全根除是困难的.
- 花的有效性是相互矛盾的;一些研究表明,当与三重疗法相结合时,可以提高根除率.
- 花提取物和硫福拉具有抗炎作用,可以减轻HP引起的粘膜损伤.
- 硫福拉衍生物并不总是影响抗生素的副作用;个体反应各不相同.
结论:
- 富含布拉西卡植物的饮食显示出对HP感染的辅助治疗的潜力,与抗生素可能具有协同作用.
- 棕植物可能有助于减轻炎症,并可能减少抗生素副作用.
- 需要进一步进行精心设计的随机试验,以确认Brassicaceae代谢物在治疗HP相关疾病中的有效性和优化使用.
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