Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

2° Amines to N-Nitrosamines: Reaction with NaNO201:20

2° Amines to N-Nitrosamines: Reaction with NaNO2

Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Identifying hepatocellular carcinoma patients at risk of early non-response after first-cycle transarterial chemoembolization: A reproducible machine learning study.

Clinical imaging·2026
Same author

Personalized whole-genome-based ctDNA dynamics during neoadjuvant therapy across breast cancer subtypes: results from MONITOR-Breast.

Future oncology (London, England)·2026
Same author

Antiviral Potential of Onosma bracteata Against Chikungunya Virus: Experimental Validation and Computational Mechanistic Study.

Applied biochemistry and biotechnology·2026
Same author

Retrospective analysis for skydiving injuries: A high-volume single-site case series.

Trauma case reports·2026
Same author

Prevalence, adherence, and health care resource utilization in schizophrenia: A national and state-level analysis of US Medicaid Beneficiaries.

Journal of managed care & specialty pharmacy·2026
Same author

RAS pathway activation and microenvironmental adaptation as hallmarks of myeloid sarcoma.

Blood cancer discovery·2026

相关实验视频

Updated: Jul 13, 2026

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
05:46

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

Published on: May 4, 2021

4.6K

氧化导致低急性综合性退行:一个案例报告

Nevin Thomas1, Ravi Patel1, Babaniji Oluwadamilola1

  • 1Internal Medicine, Methodist Dallas Health System, Dallas, USA.

Cureus
|January 1, 2025
PubMed
概括

娱乐性氧化滥用会导致维生素B12缺乏,导致亚急性综合性退行症. 早期诊断和治疗至关重要,但残留的弱点可能会持续存在,强调需要公众对这些风险的认识.

科学领域:

  • 神经学 神经学
  • 毒理学 毒理学 毒理学
  • 营养科学 营养科学

背景情况:

  • 氧化 (N2O) 由于其高兴效应,经常被滥用.
  • 长时间使用N2O可能会干扰维生素B12代谢.
  • 维生素B12缺乏与神经损伤有关,包括脱髓化.

研究的目的:

  • 报告一个与娱乐性氧化滥用相关的亚急性综合变性病例.
  • 为了强调与N2O娱乐用途相关的神经风险.
  • 倡导提高公众对N2O危险的认识和教育.

主要方法:

  • 一个31岁的男性患有神经症状的病例报告.
  • 对维生素B12缺乏症的诊断工作.
  • 肌肉内注射维生素B12治疗和物理治疗.

主要成果:

  • 这位患者出现了由于维生素B12缺乏而导致的亚急性综合性退行症.
  • 缺陷归因于六个月的休用氧化.
  • 尽管接受了治疗,但患者仍有残留的神经缺陷,需要康复.

结论:

关键词:
缺乏b12的情况.在 N2O 中, N2O 是 N2O.在SCD中,SCD是SCD.滥用物质滥用物质滥用物质滥用物质滥用物质滥用物质滥用物质鞭子的鞭子可以用作鞭子.

更多相关视频

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
07:59

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration

Published on: April 4, 2022

1.2K
Technique for Intranasal Administration of α-Synuclein Aggregates
04:49

Technique for Intranasal Administration of α-Synuclein Aggregates

Published on: November 8, 2024

345

相关实验视频

Last Updated: Jul 13, 2026

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
05:46

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

Published on: May 4, 2021

4.6K
Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
07:59

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration

Published on: April 4, 2022

1.2K
Technique for Intranasal Administration of α-Synuclein Aggregates
04:49

Technique for Intranasal Administration of α-Synuclein Aggregates

Published on: November 8, 2024

345
  • 娱乐性氧化滥用是维生素B12缺乏和随后的神经损伤的重要危险因素.
  • 亚急性综合性退行症是慢性N2O滥用的严重潜在后果.
  • 需要采取公共卫生倡议,教育人们关于滥用氧化的风险,以防止严重的发病率.