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Updated: May 7, 2025

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
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开发以醇为基础的类似物来对抗 Pseudomonas aeruginosa 感染

Taehyeong Lim1, Soyoung Ham2,3, Han-Shin Kim4

  • 1College of Pharmacy, Korea University, 2511 Sejong-ro, Sejong 30019, Republic of Korea.

ACS omega
|January 1, 2025
PubMed
概括

研究人员开发了生醇衍生物来对抗Pseudomonas aeruginosa感染. 化合物5a是一种强大的RhlR抗剂,通过向定数感应系统,有效降低了毒性因子,生物膜形成和病原性.

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