勃起功能障碍与美国男性动脉样硬化心血管疾病预测的10年风险之间的关联:来自NHANES 2001-2004的一项基于人口的研究
Yangyang Mei1, Yiming Chen2,3, Xiaogang Wang1,2,3
1Department of Urology, Jiangyin People's Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
Frontiers in endocrinology
|January 1, 2025
概括
勃起功能障碍 (ED) 与较高的动脉样硬化心血管疾病 (ASCVD) 风险得分有关. 早期ED评估可能有助于识别未来心血管事件风险的个体.
科学领域:
- 心血管医学 心血管医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 勃起功能障碍 (ED) 通常是潜在心血管疾病 (CVD) 的早期指标.
- 关于ED和CVD之间的确切关系,存在相互矛盾的证据.
- 动脉样硬化心血管疾病 (ASCVD) 风险评分为量化心血管疾病风险提供了一个工具.
研究的目的:
- 调查ED与10年ASCVD风险评分之间的关联.
- 为了确定ED是否预测了更高的ASCVD风险.
- 探索ASCVD风险与ED患病率之间的关系.
主要方法:
- 利用了1207名参与国家健康和营养检查调查 (NHANES) (2001-2004) 的数据.
- 采用加权后勤和线性回归模型来分析ED和ASCVD风险之间的关系.
- 进行了灵敏度,子组,限制立方线 (RCS) 和接收器运行特征 (ROC) 分析,以获得可靠的结果.
主要成果:
- 勃起障碍的存在与更高的ASCVD风险得分和ASCVD风险增加有关.
- 勃起障碍的存在显著增加了ASCVD风险评分 (β:2.09) 和高ASCVD风险 (OR:2.27).
- 较高的ASCVD风险类别 (边界,中等,高) 显示ED患病率逐渐增加 (ORs从2.95到18.19不等).
- RCS分析证实了ED和ASCVD风险之间的线性关系,ASCVD风险有效预测ED (AUC:0.794).
结论:
- ED可能在ASCVD的临床表现之前几年.
- 评估ED患者的心血管状况可以促进早期识别有风险的个体.
- 在ED患者的及时心血管评估允许积极实施预防策略,以改善心血管健康.
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