胆囊癌的发生频率 胆囊癌的发生频率 胆囊癌的发生频率 胆囊癌的发生频率 胆囊癌的发生频率 胆囊癌的发生频率 胆囊癌的发生频率 胆囊癌的发生频率
Muhammad Alam1, Asma Anwar1, Hikmat Ullah Qureshi2
1Department of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Cureus
|January 1, 2025
概括
胆囊癌 (GBC) 偶然地在3.04%的患者中被发现,这些患者接受了胆囊切除胆结石的手术. 症状持续时间较长和年龄较大与更高的GBC风险有关,强调需要进行病理学检查.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
背景情况:
- 胆囊癌 (GBC) 是一种罕见的,激进的癌症,通常在胆结石手术期间偶然发现.
- 由胆结石引起的慢性炎症是GBC发育的一个可疑因素.
- 在GBC患病率方面存在地理差异.
研究的目的:
- 为了确定因症状胆固醇病症而接受胆固醇切除术的患者中偶发性GBC的患病率.
- 在这个人群中确定与偶然的GBC相关的风险因素.
主要方法:
- 对230名患有症状胆病的患者 (年龄在18-55岁之间) 进行了回顾性队列研究,这些患者接受了胆囊切除术.
- 对所有切除的胆囊进行瘤组织病理学检查.
- 使用IBM SPSS (版本26) 的统计分析,p ≤0.05作为显著程度.
主要成果:
- 在3.04% (230人中7人) 的患者中检测到偶然的GBC.
- 腺癌和乳头癌是发现的主要类型.
- 与没有 (p=0.001和p=0.002) 患者相比,偶发性GBC患者年龄较大 (平均年龄49.2岁),症状持续时间较长 (平均14.2个月).
- 在手术期间没有怀疑恶性瘤.
结论:
- 在接受胆囊切除术的症状胆囊病症患者中,偶然的GBC患病率为3.04%.
- 年龄较大和症状持续时间较长是偶发GBC的重要风险因素.
- 对胆囊样本的常规组织病理学检查对于早期GBC检测至关重要,特别是在胆结石发病率高的地区.
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