多焦点性,双边性和复发的同时关联在儿科乳头甲状腺癌患者中的乳头甲状腺癌患者
Jae Won Cho1, Cheong-Sil Rah2, Won Woong Kim1
1Department of Surgery, Asan Medical Center, University of Ulsan Medical Center, Seoul, Korea.
Yonsei medical journal
|January 1, 2025
概括
多焦点性是儿科乳头甲状腺癌 (PTC) 复发的危险因素. 在4年内密切监测对于患有透明细胞亚型,多焦点和粗额外甲状腺扩张的患者至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 儿科瘤学 儿科瘤学
- 手术瘤学手术瘤学
背景情况:
- 儿科乳头甲状腺癌 (PTC) 管理通常涉及积极的手术,以减轻复发风险.
- 了解影响复发的因素对于优化年轻患者治疗策略至关重要.
研究的目的:
- 调查瘤多焦点性,双边性和儿科PTC中复发风险之间的关联.
- 确定该人群中复发的独立风险因素.
主要方法:
- 对58名患有PTC的儿科患者 (<19岁) 进行了回顾性队列研究,这些患者接受了全甲状腺切除术.
- 对临床病理学参数的分析,包括多焦点性,双边性和复发率.
主要成果:
- 多焦点性被确定为儿科PTC复发的独立风险因素 (p=0.035).
- 清晰细胞亚型和粗额外甲状腺延伸 (ETE) 也是复发的重要风险因素.
- 没有发现多焦点性和双边性之间作为对彼此呈现的独立风险因素之间存在显著的关联.
结论:
- 多焦点性,清晰细胞亚型和粗度ETE是儿科PTC复发的关键风险因素.
- 建议在甲状腺切除术后的前4年内密切监测患者是否复发,特别是在高风险人群中.
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