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Updated: Jun 4, 2025

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
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探索神经生长因子在脑缺血恢复中的细胞和分子基础

Chen-Lin Gu1, Lu Zhang2, Yan Zhu1

  • 1Institute of Translational Medicine, School of Medicine, Yangzhou University, Yangzhou 225009, China; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou University, Yangzhou 225009, China.

Neuroscience
|January 1, 2025
PubMed
概括

神经生长因子 (NGF) 在治疗血管阻塞造成的脑损伤方面表现有前途. 它保护神经元,减少炎症,并通过激活关键细胞通路来帮助恢复.

关键词:
临床应用 临床应用缺血性中风是因为缺血性中风.神经生长因子的神经生长因子神经新生是神经发生的过程.神经保护是一种神经保护.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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