过氧酸盐与Sorafenib在肝癌细胞中诱导的线粒体功能障碍有关

Patricia de la Cruz-Ojeda1, Elena Navarro-Villarán1, Marina Fuertes-Agudo2

  • 1Institute of Biomedicine of Seville (IBiS), Hospital University "Virgen Del Rocío"/CSIC/University of Seville, Seville, Spain; Department of Medical Physiology and Biophysics, University of Seville, Seville, Spain; Biomedical Research Center for Hepatic and Digestive Diseases (CIBERehd), Madrid, Spain.

PubMed
概括

索拉芬尼因增加氧化应激和损害线粒体而导致肝癌细胞死亡. 过氧化生成破坏了电子运输链的功能,影响了细胞的存活.

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