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瘤细胞异位表达IL-7的膜结合形式,在结肠癌模型中有效地发展出抗瘤免疫反应

Hee-Su Shin1, Hyejin Kim1, Soon-Gyu Kwon2

  • 1Department of Biochemistry, College of Natural Sciences, Chungnam National University, Daejeon 34134, Korea.

Molecules and cells
|January 1, 2025
PubMed
概括

在结肠癌细胞上设计的膜结合型互白素-7 (mbIL-7/B7) 减少了瘤形成,增强了全身免疫力. 这种mbIL-7/B7方法显示出有效的癌症免疫治疗的前景.

关键词:
细胞因子基因改性瘤细胞介质素-7- 介质素-7 是一种膜绑定形式 膜绑定形式瘤细胞疫苗 瘤细胞疫苗瘤治疗疗法 瘤治疗

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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