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Updated: Jun 4, 2025

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FBP1控制了老化的MASH肝细胞的肝癌演变

Li Gu1,2,3, Yahui Zhu4,5, Shuvro P Nandi6,7,8

  • 1Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA. ligu@scu.edu.cn.

Nature
|January 1, 2025
PubMed
概括

代谢功能障碍相关的脂肪肝炎 (MASH) 可能导致肝癌 (HCC). 研究人员发现,果糖-1,6-二酸酶1 (FBP1) 的下降通过促进细胞增殖和DNA突变使HCC的进展成为可能.

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