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相关概念视频

The Tongue and Taste Buds00:49

The Tongue and Taste Buds

36.4K
The surface of the tongue is covered with various small bumps called papillae, which either distribute what has been ingested (filiform papillae) or contain the sensory taste (or gustatory) receptor cells (fungiform, circumvallate, and foliate papillae). Embedded within each taste-related papilla are the taste buds—clusters of 30 to 100 gustatory receptor cells.
36.4K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

2.8K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor...
2.8K
Taste Buds and Receptors01:20

Taste Buds and Receptors

1.8K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
1.8K
Somatosensation01:33

Somatosensation

36.4K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.4K
Cranial Nerves: Types Part II01:22

Cranial Nerves: Types Part II

1.3K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
1.3K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

396
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
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相关实验视频

Updated: Jun 4, 2025

µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo
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µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo

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一个触摸指导的舌头控制的 collicular 地图

Brendan S Ito1, Yongjie Gao2, Brian Kardon2

  • 1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY, USA. itobrendan@gmail.com.

Nature
|January 1, 2025
PubMed
概括
此摘要是机器生成的。

准确的目标导向行为取决于触摸与身体位置的整合. 侧上角 (latSC) 对于动态触摸指导的舌头控制至关重要,作为机械感知运动图.

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Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells
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Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells

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Assessment of Spatial Lingual Tactile Sensitivity using a Gratings Orientation Test
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Assessment of Spatial Lingual Tactile Sensitivity using a Gratings Orientation Test

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相关实验视频

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Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells
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Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells

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科学领域:

  • 神经科学
  • 感官运动集成
  • 动物行为

背景情况:

  • 目标导向的行为需要将触觉信息与自身感知和运动结合起来.
  • 在和说话等行为中, 语言的动态控制依赖于精确的触觉事件, 但底层的神经回路是未知的.

研究的目的:

  • 调查负责动态触摸指导的舌头控制的神经回路.
  • 确定侧面上 (latSC) 在整合舌头运动的触觉和自身感知信息中的作用.

主要方法:

  • 高速度录像分析小鼠的三维语言运动.
  • 对皮层和皮下区域的功能进行光失活实验.
  • 电生理学记录以表征神经元活动的LATSC.
  • 病毒追踪和光学微刺激可以绘制神经通路和功能组织.

主要成果:

  • 鼠标集成触摸和舌头的位置重新定位当一个水口意外移动.
  • 皮层区域的光失活,但皮层区域的光失活,触摸指导的重定位受损.
  • 拉特SC神经元表现出机械感知受体场和编码的舌头位置.
  • latSC包含一个用于准的地形图,从语言三胞胎核接收输入.

结论:

  • 在动态触摸指导的舌头控制中,侧面上 (latSC) 起着至关重要的作用.
  • 拉斯卡作为一个机械感知运动地图, 整合触觉和自身感知信息, 精确的舌头运动.
  • 这些发现揭示了触摸引导的定向行为,类似于已知的视觉运动路径.