隐藏性脑梗塞的患病率和危险因素:一个基于社区的横截面研究
Ruinan Zhang1,2, Dongxiao Yao1,2,3, Xueli Cai4
1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
概括
隐性脑梗塞 (CBI) 影响9.6%的中国成年人,患病率随着年龄和高血压和高LDL-C等危险因素的增加而增加.识别这些因素对于管理这种常见的神经疾病至关重要.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 血管医学 血管医学
背景情况:
- 隐藏性脑梗塞 (CBI) 是一个普遍存在的全球健康问题,报告的患病率和风险因素不一致.
- 了解CBI的流行病学和相关因素对于公共卫生战略至关重要.
研究的目的:
- 为了确定社区成年人中CBI的患病率和风险因素.
- 调查CBI及其成像表型之间的关联.
主要方法:
- 一项基于人口的队列研究,涉及中国东南部50至75岁的2947名成年人.
- 使用3.0TMRI检测CBI和血管病变.
- 多变量后勤回归确定了CBI的独立风险因素.
主要成果:
- CBI的患病率为9.6%,其他慢性心脏病发作是最常见的亚型.
- 独立的危险因素包括年龄较大,高血压,高LDL-C,高胆固醇,高DBP,内动脉斑块和严重的外动脉样硬化负担.
- 在年龄,DBP,LDL-C和CBI几率之间观察到线性关系,而同类半氨酸显示出非线性关联.
结论:
- 在这个中国人口中,CBI的患病率是显著的.
- CBI的主要危险因素包括年龄,高血压,内动脉斑块,外动脉样硬化负担,同素,LDL-C和DBP.
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