小肠囊内镜的肠道制备:标准方案是使用2L聚乙烯糖醇与1L聚乙烯糖醇加上 Askorbate
Riccardo Caccia1, Alessandro Rimondi1, Luca Elli1,2
1Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
一种使用1L聚乙烯甘醇加酸盐 (PEG-ASC) 的新肠道制剂显示,与小肠囊内镜 (SBCE) 的标准2L PEG相比,它没有劣势. 这种制剂为优化SBCE可见性提供了可比的替代方案.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 肠道准备对于小肠囊内镜 (SBCE) 的可见性至关重要.
- 目前的指导方针建议使用2升聚乙烯糖醇 (PEG) 溶液.
- 优化SBCE肠道准备仍然是一个争论的主题.
研究的目的:
- 为了比较1L PEG加上亚酸盐 (PEG-ASC) 与SBCE标准2L PEG的疗效.
- 评估PEG-ASC对小肠粘膜可见性和诊断产量的影响.
主要方法:
- 一个随机对照试验比较2 L PEG和1 L PEG-ASC肠道准备SBCE.
- 使用小肠粘膜可见度评分系统 (SBMVSS) 评估肠道清洁度.
- 倾向性得分匹配用于创建可比的患者组.
主要成果:
- 与2L PEG (p=0.07) 相比,1L PEG-ASC改善了粘膜可见性的趋势.
- 两种制剂之间在诊断产量,整体可见性得分或完整性方面没有显著差异.
- 在所有小肠三地动物中具有相似的足够的粘膜可见性.
结论:
- 1L PEG-ASC对于小肠囊内镜制备的2L PEG是不劣的.
- PEG-ASC为优化SBCE肠道准备提供了一个潜在的有效替代方案.
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