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光学连贯断层扫描 (OCT) 和OCT血管学:脑科学中的技术发展和应用

Luyao Yang¹, Pengyu Chen¹, Xiaofei Wen¹

¹School of Pen-Tung Sah Institute of Micro-Nano Science and Technology, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Center for Molecular Imaging and Translational Medicine, Department of Vascular & Tumor Interventional Radiology, The First Affiliated Hospital of Xiamen University, School of Medicine, School of Public Health, Xiamen University, Xiamen 361102, China.

|January 2, 2025

概括

光学连贯断层扫描 (OCT) 和OCT血管扫描 (OCTA) 为脑部疾病如中风和癌症提供先进的体内成像. 人工智能和激光的未来发展有望改善大脑血液动力学和手术指导的检测.

科学领域:

神经成像是一种神经成像.
生物医学光学生物医学光学
医疗技术医疗技术医学技术

背景情况:

大脑疾病对全球健康构成重大负担,导致广泛的残疾和死亡率.
早期诊断对于及时干预和改善患者预后至关重要.
光学连贯断层扫描 (OCT) 和OCT血管扫描 (OCTA) 提供高分辨率的体内3D微血管成像.

研究的目的:

审查最近光学连贯断层扫描 (OCT) 和OCT血管造影 (OCTA) 在活人脑部成像方面的进展.
讨论OCT/OCTA在各种神经疾病中的应用.
确定当前的挑战和该领域的未来方向.

主要方法:

对脑成像的OCT和OCTA技术的当前文献的综述.
对中风,创伤性脑损伤 (TBI) 和脑癌中的OCT/OCTA应用进行分析.
讨论技术模式和理论方法.

主要成果:

在生物体内,OCT/OCTA可实现大脑的非侵入性,高分辨率的3D微血管成像.
这些技术在研究和诊断中风,TBI和脑瘤方面表现有前途.
目前的局限性存在,但正在进行的技术发展值得注意.

结论:

OCT/OCTA是体内脑部成像的宝贵工具,提供毛细血管级分辨率.
持续的进步,特别是激光技术和人工智能,预计将提高诊断能力.
未来的应用可能包括精确检测深度大脑血液动力学和瘤切除的手术内指导.

关键词:

大脑癌症脑癌脑癌缺血性中风中风光学连贯性断层扫描 (optical coherence tomography) 是一种光学连贯性断层扫描技术.创伤性脑损伤是一种创伤性脑损伤

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