术前口服类固醇对鼻多症患者的结果
Sukriti Nehra1, Bikram Choudhury2, Amit Goyal2
1Department of Otorhinolaryngology, PGI Satellite Centre, Sangrur, India.
概括
手术前的口服普雷迪尼索隆并没有显著改善鼻多重症手术的结果. 这项随机对照试验在接受类固醇和接受安慰剂的患者之间没有发现手术内或术后参数的显著差异.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻炎研究研究 鼻炎研究
- 外科手术的结果
背景情况:
- 鼻多重症 (SNP) 显著影响生活质量.
- 功能性内镜外科手术 (FESS) 是SNP的常见治疗方法.
- 术前口服类固醇在优化FESS结果中的作用受到争议.
研究的目的:
- 评估手术前口服普雷迪尼索隆在改善SNP的FESS患者的手术内参数和3个月的术后结果方面的疗效.
主要方法:
- 这是一项随机对照试验,涉及43名SNP患者.
- 使用经过验证的评分系统 (SNOT-22,Lund-Mackay,DIP,Lund-Kennedy,POSE) 进行手术前,手术期间和手术后3个月的评估.
- 在普雷迪尼索隆和安慰剂组之间的手术持续时间,血液损失和视觉模拟尺度得分的比较.
主要成果:
- 在手术持续时间或手术内参数方面没有观察到统计学意义上的差异.
- 手术后的中鼻结局测试 (SNOT-22) 在普雷迪尼索隆组没有显著改善.
- 实验组和对照组之间的任何评估结果参数都没有显著差异.
结论:
- 在SNP的FESS中,手术前的口服普雷迪尼索隆对手术内或术后的结果没有显著的益处.
- 研究结果表明,在SNP患者手术结果改善方面,可能不需要定期使用手术前的口服类固醇.
- 进一步的研究可能会探索特定的患者亚组或替代性类固醇治疗方案.
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