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Updated: May 7, 2025

Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice
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Published on: February 17, 2023

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通过LEF1/SEMA7A/PI3K-AKT,NCAPG促进子宫内膜癌恶性进展

Zhen Ren1, Xiaohan Li1, Chun Fu1

  • 1Department of Obstetrics and Gynecology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.

Journal of Cancer
|January 2, 2025
PubMed
概括

NCAPG通过影响LEF1结合和SEMA7A转录来驱动子宫内膜癌 (EC) 的进展,最终激活PI3K-AKT通路. 这个NCAPG/LEF1/SEMA7A轴为EC提供了潜在的治疗目标.

关键词:
在LEF1中,我们可以使用LEF1在NCAPG中,我们可以使用NCAPG.在PI3K/AKT信号通路中.这就是SEMA7A的意义.胚胎内膜腺癌 (Endometrioid Carcinoma) 是一个癌症.

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