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Updated: May 7, 2025

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通过在Magnaporthe oryzae中准CPKA蛋白来提高爆病免疫力 (M. oryzae) 与天然化合物一起使用

Nimai Charan Mahanandia1,2, Satyaranjan Biswal3, Dwijesh Chandra Mishra2

  • 1The Graduate School, ICAR-Indian Agricultural Research Institute (IARI), Pusa, New Delhi, India.

Journal of biomolecular structure & dynamics
|January 2, 2025
PubMed
概括

天然化合物尼蒙醇和黄素通过向Magnaporthe oryzae中的CPKA蛋白来抑制大米爆发病的前景. 需要进一步的研究来探索它们作为有效的病抑制剂的潜力.

关键词:
这就是CPKA的CPKA.在M. oryzae的研究中.模拟MD的模拟方法在MM-PBSASA中使用.分子对接的分子对接.

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Cyclic Adenosine Monophosphate (cAMP) is an essential second messenger that activates protein kinase A (PKA) and regulates various biological processes. A single epinephrine molecule binds to GPCR and activates several heterotrimeric G proteins, each stimulating multiple adenylyl cyclase, amplifying the signal, and synthesizing large numbers of cAMP molecules. Small changes in cAMP concentration affect PKA activity. The binding of four cAMP molecules induces a conformational change in PKA,...
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