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Updated: May 3, 2026

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TarIKGC:一个使用语义增强知识图表完成的目标识别工具,应用到CDK2抑制剂发现

Xiaojuan Shen1, Shijia Yan1, Tao Zeng1

  • 1State Key Laboratory of Anti-Infective Drug Discovery and Development, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

Journal of medicinal chemistry
|January 2, 2025
PubMed
概括

我们开发了TarIKGC,这是一种用于药物发现的新工具,它使用知识图表完成来改善化合物-标相互作用预测. TarIKGC成功地确定了具有抗增殖活性的潜在CDK2抑制剂.

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