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在Streptomyces avermitilis中,基于高通量查和中等优化,改善了多拉克的产生

Yu Wang1,2, Huan He2, Siqi Li1

  • 1College of Chemical Engineering, Shijiazhuang University, Shijiazhuang, Hebei Province, China.

Preparative biochemistry & biotechnology
|January 2, 2025
PubMed
概括

研究人员开发了一种高产的突变菌株Streptomyces avermitilis,用于增加多拉克的产量. 这种增强的菌株和优化的发酵实现了这一重要的抗寄生虫药物报告的最高产量.

关键词:
大气和室温等离子体 (ARTP)多拉美克丁 (Dor) 是一种药物.杆菌 (Streptomyces avermitilis) 是一种杆菌.高通量选的高通量选中等优化优化 介质优化响应表面方法 (RSM)

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