超声指导的皮肤穿透核心针活检用于诊断1型自身免疫性胰腺炎
Qiyu Zhao1, Weilu Chai1, Xinyan Jin1
1First Affiliated Hospital Zhejiang University, Hangzhou, China.
Abdominal radiology (New York)
|January 2, 2025
概括
超声指导的核心针活检 (US-CNB) 有效诊断1型自身免疫性胰腺炎 (AIP). 将US-CNB添加到诊断过程中显著改善了最终的1型AIP诊断率,并导致了高缓解率.
科学领域:
- 胃肠病学 胃肠病学
- 诊断成像 诊断成像 诊断成像
- 病理学 病理学 病理学
背景情况:
- 自身免疫性胰腺炎 (AIP) 是一种慢性炎症性疾病.
- 准确诊断1型AIP对于有效管理至关重要.
- 当前的诊断方法在检测特征性组织学特征时可能存在局限性.
研究的目的:
- 评估超声导向的核心针活检 (US-CNB) 在诊断1型AIP时的实用性.
- 为了评估类型1AIP患者在类固醇治疗后的放射性结果.
主要方法:
- 从2017年1月到2023年6月对患有"淋巴细胞透"和"纤维化"的患者进行了回顾性研究.
- 评估国际共识诊断标准 (ICDC) 1级组织学检测率.
- 评估了US-CNB对最终1型AIP诊断的贡献.
- 分类的放射性反应的类固醇治疗后的活检.
主要成果:
- 美国-CNB改善了确定的1型AIP的诊断率,从44.3%提高到67.2% (p=0.017).
- 包括类固醇试验在内的整体诊断率达到91.8%.
- 在12个月的随访中,48名患者对类固醇治疗产生了良好的放射性反应.
结论:
- 超声导向的核心针活检是诊断1型AIP的宝贵工具.
- 将US-CNB纳入诊断算法可以更好地识别1型AIP.
- 在使用这种增强诊断方法治疗的1型AIP患者中观察到高缓解率.
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