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验证规则 定义 没有改善 视觉敏度 在 儿童 眼 儿童 眼
Rui Wu1, Ruth E Manny2, Jonathan M Holmes3
1Jaeb Center for Health Research, Tampa, Florida, United States.
Investigative ophthalmology & visual science
|January 2, 2025
概括
在眼治疗中确定稳定的视敏度 (VA) 对于决策至关重要. 这项研究评估了VA稳定性的规则,根据使用的方法发现了显著的虚假阴性和虚假阳性率.
科学领域:
- 眼科医生 眼科 眼科
- 儿科医学 儿科医学
- 临床研究 临床研究
背景情况:
- 眼的治疗需要准确确定视敏度 (VA) 的稳定性.
- 治疗决策,如继续或改变诸如补丁或眼镜之类的干预措施,取决于VA是否平稳.
研究的目的:
- 评估不同规则的准确性,以确定眼敏度的稳定性.
- 通过各种测量和分析方法来比较VA稳定性的假阳性和假阴性率.
主要方法:
- 模拟观察到的VA,包括测量误差,与模拟的真实VA进行了比较.
- 测试了六个不同的规则来评估VA稳定性,使用单次或测试/重新测试测量在两个或三个访问,或没有平均值.
- 模拟了四种野眼形状 (稳定或改善VA) 用于补丁和眼镜治疗.
主要成果:
- 当真正的VA稳定时,稳定性的假负率在26%至67%之间.
- 当真实VA正在改善时,稳定性虚假阳性率在0%至38%之间.
- 与单次测量相比,平均每次访问两次VA测试减少了假阳性率,但略有增加了假阴性率.
结论:
- 确定VA稳定性的规则选择会影响临床和研究结果.
- 当考虑不太理想的治疗方法时,更低的虚假负率是首选的,而更低的虚假阳性率更好地准确地分类改善VA.
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