在产后12个月内与保持艾滋病毒护理相关的因素:回顾性队列研究
Tran Dang1, Jean Anderson, Anna M Powell
1Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD.
Journal of acquired immune deficiency syndromes (1999)
|January 2, 2025
概括
产后艾滋病毒护理保留率高达83.8%,但怀孕期间的物质使用成为失去随访的重要风险因素. 持续参与艾滋病毒治疗对于预防疾病进展至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 妇女健康 妇女健康
背景情况:
- 在产后艾滋病毒护理中失去随访增加了病毒非抑制,疾病进展和艾滋病毒传播的风险.
- 识别与保留相关的因素对于改善生育父母感染艾滋病毒的结果至关重要.
研究的目的:
- 评估与产后人体免疫缺陷病毒 (HIV) 护理保留相关的因素.
- 确定在分娩后继续参与艾滋病毒护理服务的预测因素.
主要方法:
- 从2014年1月到2022年12月,对111名患者进行了回顾性队列研究.
- 主要结局:在12个月内保持产后艾滋病毒治疗 (根据艾滋病毒药物坚持或病毒载荷遭遇定义).
- 统计分析包括千二测试,t测试和后勤回归模型.
主要成果:
- 83.8%的参与者 (93/111) 在产后12个月内继续接受艾滋病毒治疗.
- 保留与产前抗逆转录病毒疗法 (ART) 使用和分娩时的病毒抑制有关.
- 怀孕期间的物质使用与产后艾滋病毒护理保留 (aOR 0.29) 有负相关性.
结论:
- 近84%的艾滋病毒感染者获得了产后护理.
- 怀孕期间的物质使用是产后艾滋病毒护理流失的重要风险因素.
- 对于有药物使用史的人来说,可能需要针对性的干预措施来改善保留.
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