产前,分娩和产后静脉血栓栓塞的趋势
Olivia Kola1, Yongmei Huang, Mary E D'Alton
1Rutgers New Jersey Medical School, Newark, New Jersey; the Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, New York; and the Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California.
Obstetrics and gynecology
|January 2, 2025
概括
从2009年到2019年,产科静脉血栓栓塞 (VTE) 的风险显著增加. 这种增加发生在整个怀孕期间,包括阴道和剖腹产分娩的产前,分娩和产后时期.
科学领域:
- 产科和妇科 产科和妇科
- 心血管健康 心血管健康
- 公共卫生 公共卫生
背景情况:
- 产科静脉血栓塞栓症 (VTE) 是孕产妇发病率和死亡率的一个重要原因.
- 了解怀孕期间VTE风险的趋势对于有效的预防和管理策略至关重要.
研究的目的:
- 评估从2008年到2019年产科静脉血栓塞栓症 (VTE) 风险的时间趋势.
- 为了确定怀孕期间具有最高VTE风险和相关风险因素的时期.
主要方法:
- 回顾性队列研究分析了美国大型索赔数据库 (2008-2019).
- 包括年龄在15-54岁的妇女,分娩时住院和持续医疗保健入学.
- 结点回归分析了VTE趋势;日志-波松回归评估了风险因素关联.
主要成果:
- 在怀孕期间观察到VTE风险显著增加,平均年百分比变化 (APC) 为9.2%.
- 在产前 (APC 8.2%),分娩 (APC 12.2%) 和产后 (APC 8.4%) 期间,VTE风险增加.
- 肥胖,慢性心脏病,吸烟,喘和孕前与增加静脉瘤风险显著相关.
结论:
- 在研究期间,产科VTE风险显著增加.
- 在整个怀孕期间,VTE风险升级,包括产前,分娩和产后阶段.
- 识别和管理诸如肥胖和妊娠前等危险因素对于减轻产科VTE至关重要.
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