代谢功能障碍在创伤性脑损伤后导致情绪障碍
Lang Liu1, Peijun Jia2, Tongzhou Liu3
1Department of Pain Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Ageing research reviews
|January 2, 2025
概括
创伤性脑损伤 (TBI) 可以导致由于代谢变化的情绪障碍. 解决这些代谢功能障碍可能有助于缓解创伤后的焦虑和抑郁.
科学领域:
- 神经科学是一个神经科学.
- 代谢障碍 代谢障碍 代谢障碍
- 精神病学是一个精神病学.
背景情况:
- 创伤性脑损伤 (TBI) 是导致死亡和残疾的主要原因.
- 伤心创伤幸存者经常经历情绪障碍,如焦虑和抑郁.
- 氨基酸,脂质,铁,和铜的代谢障碍与这些情绪障碍有关.
研究的目的:
- 审查代谢功能障碍对TBI后情绪障碍的影响.
- 探索TBI后焦虑和抑郁症的治疗策略.
- 突出特定代谢途径和元素的作用.
主要方法:
- 对PubMed和Web of Science数据库的文献评论.
- 专注于将代谢功能障碍与创伤后情绪障碍联系在一起的机制.
- 重点是谷氨酸,金氨酸,脂质,铁,和铜的新陈代谢.
主要成果:
- 代谢功能障碍通过谷氨酸和金氨酸途径导致情绪障碍.
- 内分类固醇,铁沉积,铁,缺乏和铜失调都与此有关.
- 此外,还讨论了代谢功能障碍对老年TBI人口情绪障碍的影响.
结论:
- 代谢功能障碍是TBI后情绪障碍的一个重要因素.
- 针对代谢途径提供了一个有前途的治疗策略.
- 纠正代谢失衡是治疗创伤后焦虑和抑郁的可行方法.
相关概念视频
Bipolar Disorder
52
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
52
Depression: Overview
213
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
213
Post-traumatic Stress Disorder
27
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
27
Brain Imaging
208
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
208


