烟草吸烟和症状负担:九个ECOG-ACRIN癌症临床试验的基线结果
Sarah N Price1, Ju-Whei Lee2, Ilana F Gareen3
1Wake Forest University School of Medicine (S.N.P., L.I.W.), Winston-Salem, North Carolina, USA.
Journal of pain and symptom management
|January 2, 2025
概括
吸烟的癌症幸存者报告了更糟糕的症状,如咳和疼痛,并错误地认为吸烟有助于控制恶心和失眠. 戒烟对于癌症患者的症状管理至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 行为科学 行为科学
背景情况:
- 大约11%的癌症幸存者在诊断后继续吸烟.
- 了解吸烟与症状感知之间的联系对于在这个人群中进行有效的烟草治疗干预至关重要.
研究的目的:
- 为了调查吸烟状态和癌症相关症状的经验之间的关系.
- 探索当前吸烟如何影响症状严重程度和感知症状缓解.
主要方法:
- 分析了9项ECOG-ACRIN试验 (2017-2021) 中740名成年参与者的数据.
- 使用后勤回归来评估吸烟状态对症状的影响,控制人口统计和临床因素.
- 费舍尔的确切测试比较了现在和前吸烟者之间的症状感知.
主要成果:
- 当前吸烟者报告说,与以前或从未吸烟者相比,出现咳的可能性显著更高.
- 吸烟与咳和疼痛的严重程度增加,以及更大的疼痛干扰有关.
- 与前吸烟者相比,目前吸烟者更有可能相信吸烟有助于控制恶心,失眠和疼痛.
结论:
- 癌症幸存者目前的吸烟与症状严重程度 (咳,疼痛) 的增加以及对吸烟作为应对机制的误解有关.
- 综合性症状管理计划必须包括戒烟,患者教育吸烟相关症状恶化,以及其他缓解策略.
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