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Updated: Jun 4, 2025

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随机森林算法揭示了HA蛋白中的新型位点,这些位点改变了H9N2禽流感病毒的受体结合偏好

Yuncong Yin1, Wen Li2, Rujian Chen2

  • 1College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou University, Yangzhou 225009, China; International Joint Laboratory for Cooperation in Agriculture and Agricultural Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China.

Virologica Sinica
|January 2, 2025
PubMed
概括

禽流感病毒可以通过切换到人类受体引起大流行. 这项研究确定了H9N2禽流感病毒中关键的血凝素突变,使其能够与人类受体结合,构成公共卫生威胁.

关键词:
在H9N2疫情下,血凝素 (HA) 是一种东道主转班的时间.跨物种的传播方式随机森林算法 随机森林算法接收器绑定偏好 接受器绑定偏好

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