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美国因炎症性肠病导致的死亡率趋势:一个CDC奇迹数据库分析 (1999-2020)
Syed Sarmad Javaid1, Shanzay Akhtar2, Areesha Hafeez2
1Department of Medicine, University of Mississippi Medical Center, Jackson, USA. ssjavaid@umc.edu.
Digestive diseases and sciences
|January 2, 2025
概括
炎症性肠病 (IBD) 死亡率在2018年之前下降,然后在克罗恩病和性结肠炎中显著增加. 针对这些IBD趋势,需要针对性的干预措施.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 炎症性肠病 (IBD) 构成了全球重大健康挑战,美国患病率最高.
- 了解人口和区域死亡趋势对于公共卫生倡议至关重要.
研究的目的:
- 分析1999年至2020年美国炎症性肠病 (IBD) 相关死亡率的人口和区域趋势.
- 为了识别随着时间的推移,克罗恩病和性结肠炎的年龄调整死亡率 (AAMR) 的变化.
主要方法:
- 使用CDC奇迹数据库来获取IBD死亡率数据 (1999-2020年).
- 每10万人口的年龄调整死亡率 (AAMR) 计算.
- 雇员Joinpoint回归分析趋势变化和年度百分比变化 (APC).
主要成果:
- 总共有62,310例IBD相关死亡记录.
- 从1999年至2018年,IBD死亡率下降,然后从2018年至2020年急剧增加.
- 在人口统计学 (性别,种族) 和美国各州之间观察到死亡率的显著差异.
结论:
- 2018年左右,IBD死亡率趋势发生了显著的转变,随后的增加.
- 迫切需要针对性的公共卫生干预措施,以应对日益增加的IBD死亡率.
- 对最近死亡率上升的原因进行进一步研究是有必要的.
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