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Updated: Jun 4, 2025

Computational Analysis of the Caenorhabditis elegans Germline to Study the Distribution of Nuclei, Proteins, and the Cytoskeleton
08:01

Computational Analysis of the Caenorhabditis elegans Germline to Study the Distribution of Nuclei, Proteins, and the Cytoskeleton

Published on: April 19, 2018

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一个更高阶的PUF复合体是C. elegans生殖干细胞调节的核心

Chen Qiu1, Sarah L Crittenden2, Brian H Carrick2,3

  • 1Epigenetics and RNA Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.

Nature communications
|January 2, 2025
PubMed
概括

PUF蛋白 FBF-2 和伴侣 LST-1 形成了一个复合物,该复合物调节生殖系干细胞 (GSC) 中的基因表达. 这个复合体控制RNA抑制和激活,影响干细胞的维持和分化.

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In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay08:56

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Detecting Protein Subcellular Localization by Green Fluorescence Protein Tagging and 4',6-Diamidino-2-phenylindole Staining in Caenorhabditis elegans09:36

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