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Updated: Jun 4, 2025

Analysis of RNA Processing Reactions Using Cell Free Systems: 3' End Cleavage of Pre-mRNA Substrates in vitro
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人类核和线粒体tRNA 3'处理的分子基础

Arjun Bhatta1,2,3, Bernhard Kuhle1,2, Ryan D Yu1,2,3

  • 1Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.

Nature structural & molecular biology
|January 2, 2025
PubMed
概括

人类ELAC2酶过程转移RNA (tRNA) 前体. 对于线粒体tRNAs (mt-tRNAs),它需要TRMT10C和SDR5C1,特别是对于结构异常的mt-tRNAs,揭示了对tRNA成熟的新见解.

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