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Updated: Jun 4, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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基于多个物种对齐的DNA语言模型预测了全基因组变异的影响

Gonzalo Benegas1,2, Carlos Albors2, Alan J Aw3

  • 1Graduate Group in Computational Biology, University of California, Berkeley, CA, US.

Nature biotechnology
|January 3, 2025
PubMed
概括

我们开发了GPN-MSA,这是一个具有多个序列对齐的新型基因组预训网络,以准确预测遗传变异对整个人类基因组的影响,包括非编码区域.

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