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Updated: Jun 4, 2025

Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
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TRIM32通过控制肝脏胰岛素受体降解来调节胰岛素敏感性

Shilpa Thakur1, Priya Rawat1, Budheswar Dehury2

  • 1School of Biosciences and Bioengineering, Indian Institute of Technology Mandi, Mandi, 175005, H.P., India.

EMBO reports
|January 3, 2025
PubMed
概括

三方基因含蛋白32 (TRIM32) 通过降低肝脏中的胰岛素受体 (INSR) 来驱动与肥胖相关的胰岛素耐药性. 在高脂肪饮食模型中,减少TRIM32可以改善胰岛素敏感性和肝脏健康.

关键词:
胰岛素受体 胰岛素受体胰岛素耐药性 胰岛素耐药性是一种在SREBP-1cc中.在TRIM32中,我们可以使用TRIM32.在Ubiquitination中使用.

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