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Updated: Jun 4, 2025

Automated Sholl Analysis of Digitized Neuronal Morphology at Multiple Scales
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Published on: November 14, 2010

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第五层金字塔神经元的突触信号和疾病脆弱性

Gabriele Marcassa1,2, Dan Dascenco1,2, Blanca Lorente-Echeverría1,2

  • 1VIB Center for Brain & Disease Research, Leuven, Belgium.

Nature communications
|January 3, 2025
PubMed
概括

研究人员在小鼠大脑细胞中鉴定出不同的突触蛋白,揭示了 intratelencephalic (IT) 和pyramidal tract (PT) 神经元之间的差异. 这一发现凸显了自闭症等神经系统疾病的潜在分子标.

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Synaptic Signaling

Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
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The presynaptic neuron fires an action potential that...
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Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
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Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
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