与心血管疾病相关的因素和心血管疾病的风险在没有控制高血压的人
Sara Ringwald-de Meyer1, Roxane de La Harpe2, Peter Vollenweider2
1Department of Medicine, Division of Internal Medicine, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland. svdemeyer@gmail.com.
Scientific reports
|January 3, 2025
概括
失控的高血压与大量饮酒,肥胖和教育水平有关. 研究人员确定了与失控血压相关的关键因素,这表明了早期识别和干预策略的潜力.
科学领域:
- 心血管健康 心血管健康
- 高血压研究 高血压研究
- 公共卫生 公共卫生
背景情况:
- 高血压是一个全球性的健康问题,失控的病例带来了重大风险.
- 识别与不受控制的高血压相关的因素对于有效的管理和预防至关重要.
研究的目的:
- 识别和验证与不受控制的高血压相关的因素.
- 评估未经控制的高血压与心血管疾病和全因死亡率的潜在关联.
主要方法:
- 分析了1040名参与者从科劳斯和PsyCoLaus研究 (2003-2006).
- 研究了高血压状态 (无控制与控制) 和潜在风险因素之间的关联.
- 在12.3年的随访期间,对未经控制的高血压与心血管疾病和死亡率的联系进行前性评估.
主要成果:
- 过度饮酒,身体质量指数 (BMI) 增加,费里丁含量升高和白尿与不受控制的高血压有积极的关联.
- 大学学位,目前的吸烟和高尿分泌与不受控制的高血压相反相关.
- 在这个队列中,不受控制的高血压与发生的动脉样硬化心血管疾病 (ASCVD) 或全因死亡率没有显著关联.
结论:
- 失控的高血压与可改变的生活方式因素有关,包括大量饮酒,肥胖和教育程度.
- 尿路,费里丁和白尿等生物标记物可能有助于识别患有失控高血压风险的个体.
- 需要进一步的研究来探索这些生物标记物在早期高血压管理中的临床实用性.
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