来自生物质废弃物的发光碳点,用于在片剂剂型中灵敏地确定甲酸
Nehal Mohamed1, Mahmoud Hamed1,2, Fotouh R Mansour3
1Pharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University, Cairo, Egypt.
概括
这项研究开发了一种绿色光谱计法,使用来自南瓜种子废弃物的天然碳量子点进行酸分析. 环保方法为质量控制提供了一个灵敏,准确和具有成本效益的替代方案.
科学领域:
- 分析化学 分析化学
- 材料科学 材料科学 材料科学
- 绿色化学 绿色化学
背景情况:
- 目前的 Askorbic 酸 (ASA) 分析方法通常是复杂的,缓慢的,需要危险的化学物质.
- 需要为ASA质量控制提供负担得起,环保和高效的分析技术.
研究的目的:
- 为ASA量化开发一种绿色光谱法.
- 从南瓜种子皮 (PSP) 中合成自然碳量子点 (NACQD),作为光探针.
- 评估该方法的性能和环保性.
主要方法:
- 从PSP中使用微波辅助方法合成NACQD.
- 使用TEM,SEM,EDX和FTIR进行NACQD的表征.
- 基于NACQDs的光灭ASA的光谱光测量分析.
- 验证该方法的线性,灵敏度,准确性和精度.
主要成果:
- 基于PSP的NACQD成功合成和表征.
- 开发的方法显示出极好的线性 (r=0.996) 和灵敏度 (LOD=0.1μg/mL,LOQ=0.3μg/mL).
- 高精度 (99.36%-100.35%恢复) 和精度 (<0.21% RSD) 在ASA量化方面得到了实现.
- 这种方法成功地应用于ASA药片配方.
结论:
- 使用NACQD开发的绿色光谱法是一种敏感,准确和具有成本效益的ASA分析方法.
- 这种方法为传统技术提供了一种实用且环保的替代方案.
- 使用像PSP这样的废物材料用于NACQD合成与绿色化学原则保持一致.
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