相关实验视频

Updated: Jun 4, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

在两个以人口为基础的英国队列中,食物过敏的患病率分别在12年间出生

William Fong¹, Kaci Pickett-Nairne², Manzi Venter³

¹Sheffield Teaching Hospital, Sheffield, UK.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

|January 3, 2025

概括

超过10年的儿童中,食物过敏和反应的发生率保持稳定. 这项研究发现,在英格兰的两个出生队伍之间,食物过敏患病率没有显著增加.

科学领域:

儿科过敏和免疫学
食物过敏的流行病学食物过敏的流行病学
免疫媒介疾病免疫媒介疾病

背景情况:

食物不良反应包括免疫媒介的食物过敏 (FA) 和非免疫媒介的食物不耐受.
食物过敏分为IgE介导型和非IgE介导型.
关于食物过敏患病率的时间趋势的数据有限.

研究的目的:

为了比较不良食物反应,食物敏感化和确诊的食物过敏的患病率.
为了评估两个分隔12年的出生队伍之间这些条件的变化.
在生命的第一个十年内调查儿科食物过敏的趋势.

主要方法:

研究了来自英国怀特岛的两个出生队伍,分别出生12年 (1989-1990年和2001-2002年).
父母报告的不良食物反应,过敏敏感化和确诊的FA在1,2,3,4岁和10岁时被评估.
在评估中包括了IgE和非IgE介导的FA.

主要成果:

报告的不良食物反应和敏感率在两个队列之间是相似的.
经确认的食物过敏患病率显示,在1岁,2岁和3至4岁的后期队列 (FAIRBC) 中,较低的患病率的趋势不显著.
确定的牛奶过敏在早期队列 (IOWBC) 中在3岁时更高,但在其他时间点没有.

结论:

该研究没有发现对不良食物反应,食物敏感性或食物过敏率的显著变化的证据.
儿童食物过敏的患病率在两个研究的队列之间,在生命的前10年保持稳定.
这些发现有助于了解食物过敏随时间推移的流行病学.

关键词:

这是FAFAFAFAFA.童年的童年童年的童年儿科儿科儿科患病率的流行情况.时间变化,时间变化.

更多相关视频

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

相关概念视频

Allergic Reactions

Allergic Reactions

Cross-reactivity

Cross-reactivity

Hypersensitivities

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

Nature and Nurture

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...