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Updated: May 7, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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FTDMP:一种蛋白质-蛋白质,蛋白质-DNA和蛋白质-RNA对接和评分的框架.

Kliment Olechnovič1,2, Rita Banciul1, Justas Dapkūnas1

  • 1Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania.

Proteins
|January 3, 2025
PubMed
概括

FTDMP是一种用于生物分子对接和评分的多功能软件框架. 它有助于建模蛋白质,DNA和RNA相互作用,在盲测试和基准测试中证明有效.

关键词:
停靠的对接方式质量评估模型质量评估模型蛋白质复合体 蛋白质复合体蛋白质蛋白质相互作用获得得分的得分.

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Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
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