韩国成年人的阻塞性睡眠呼吸暂停和白膜尿之间的关联:全国人口研究
Yeojin Yu1, Kyungdo Han2, Kyu-Na Lee3
1Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Kidney research and clinical practice
|January 3, 2025
概括
专尿,损伤的标志物,与阻塞性睡眠呼吸暂停 (OSA) 的更高风险有关. 早期的OSA查对于患有白蛋白尿症的患者来说至关重要,以改善健康结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与心血管和代谢问题有关.
- 膜尿,损伤的指标,被认为是OSA的危险因素.
- 这项研究调查了韩国成年人的OSA-albuminuria联系.
研究的目的:
- 探索白膜尿和阻塞性睡眠呼吸暂停 (OSA) 之间的关联.
- 为了确定白色素尿是否是韩国成年人OSA的危险因素.
- 为了检查白尿严重程度与OSA风险之间的关系.
主要方法:
- 利用了韩国国家健康和营养检查调查 (2019-2021) 的数据.
- 包括10,923名40岁以上的参与者,他们填写了STOP-BANG问卷.
- 通过尿液中白蛋白与肌素的比率 (≥30 mg/g Cr) 确定白尿,并使用后勤回归.
主要成果:
- 专尿与增加OSA风险显著相关 (OR 2.01).
- 专尿和OSA风险之间的关联随着专尿严重程度的增加而加剧.
- 观察到一种双向关系,高的OSA风险得分与更高的白尿概率相关 (OR 2.51).
结论:
- 专尿明显与阻塞性睡眠呼吸暂停的风险增加有关.
- 建议对阿尔伯米努里亚患者进行早期的OSA查,特别是那些有代谢风险因素的人.
- 强调管理这两种疾病的重要性,以获得更好的长期患者结果.
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