甲膜类型对跨导管大动脉置换后血管和出血并发症的影响:来自MARVEL注册研究的后期分析
Emily Pan1,2, Herbert G Kroon3, Pim A L Tonino4
1Department of Surgery, Central Finland Hospital Nova, Jyväskylä, Finland.
概括
使用MANTA关闭的输管外导管大动脉置换术 (TAVR) 后的血管并发症不受外套类型的影响. 然而,可扩展的盖子可以显著减少血液静止的时间.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 血管外科 血管外科
背景情况:
- 血管和出血并发症是转管透导体大动脉置换 (TAVR) 后的重大问题.
- 不同类型对这些并发症率的影响仍然不完全理解.
研究的目的:
- 为了比较在输血TAVR期间可扩展和常规外套之间的血管和出血并发症率.
- 为了评估外套类型对MANTA血管闭塞装置部署后血液静止的时间的影响.
主要方法:
- 未来的MARVEL注册研究包括500名接受大孔输血手术的患者,MANTA设备关闭.
- 根据护套类型 (可扩展与常规) 患者进行了分层.
- 倾向匹配分析评估了VARC-2血管和出血并发症,以血静止的时间为次要终点.
主要成果:
- 分析了196对与倾向相匹配的对.
- 在可扩展和常规组之间,在主要 (3.6%与4.1%) 或轻微 (5.6%与4.6%) 血管并发症中没有显著差异.
- 出血并发症的发生率相似,但血液静止的时间在可扩展罩 (30s vs. 60s) 时显著缩短.
结论:
- 曼塔动脉切除关闭显示了可比的血管并发症率,无论使用可扩展或传统的大孔罩.
- 可扩展与显著更快的血液静止时间有关,可能会提高程序效率.
相关概念视频
01:24Disorders of Hemostasis
696
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
696
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
607
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
607