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Updated: Jul 3, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
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高效的双探针策略,用于单细胞代谢物分析

Lvyang Zhu1, Majun Yang1, Qu Tang1

  • 1School of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, P. R. China.

Analytical chemistry
|January 3, 2025
PubMed
概括

这项研究引入了一种微流体平台,用于单细胞代谢分析,以了解癌症转移. 它揭示了细胞代谢和转移相关因素之间的相关性,有助于治疗开发.

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Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
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High-Performance Liquid Chromatography: Types of Detectors

The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...