怀孕期间腹部脂肪组织和子宫外脂肪储存的变化与妊娠期体重增加分离
Christina Sonne Mogensen1, Faidon Magkos1, Elizaveta Chabanova2
1Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Obesity (Silver Spring, Md.)
|January 3, 2025
概括
超重/肥胖妇女的妊娠期体重增加与腹部脂肪的变化有关. 虽然怀孕期间内脏和皮下脂肪组织减少,但GWG特别影响皮下脂肪.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 代谢健康 代谢健康
- 医疗成像医学成像
背景情况:
- 在怀孕期间超重和肥胖与不良结果有关.
- 了解怀孕期间脂肪组织的变化对于母亲的健康至关重要.
- 宫外脂肪积累可能会影响代谢健康.
研究的目的:
- 为了评估怀孕期间腹部脂肪组织和子宫外脂肪的变化.
- 为了研究妊娠期体重增加 (GWG) 和这些脂肪储存之间的关系.
- 专注于超重/肥胖妇女.
主要方法:
- 一个随机对照试验的二次分析.
- 磁共振成像 (MRI) 在妊娠15周,32周和出生前.
- 量化皮下脂肪组织 (SAT),内脏脂肪组织 (VAT),肝脂肪和肌肉脂肪.
主要成果:
- 增值税和SAT从妊娠第15周下降到第32周,在出生时反弹,但仍然低于基线.
- 没有观察到肝脏或肌肉脂肪的显著变化.
- GWG与SAT的变化有积极的相关性,但不是VAT,肝脏或肌肉脂肪.
结论:
- 怀孕对超重/肥胖妇女的腹部脂肪储存有动态变化.
- 怀孕期间减少VAT和SAT,GWG与SAT相关,可能表明怀孕体重增加的代谢有害影响较小.
- 需要对潜在机制和长期健康影响进行进一步的研究.
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