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Updated: May 7, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

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贝叶斯效应大小排名来优先考虑常见疾病中的遗传风险变体,用于后续研究

Daniel J M Crouch1, Jamie R J Inshaw1, Catherine C Robertson2

  • 1JDRF/Wellcome Diabetes and Inflammation Laboratory, Nuffield Department of Medicine, Centre for Human Genetics, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.

Genetic epidemiology
|January 3, 2025
PubMed
概括

我们推出优先FDR,一种结合效果大小和统计学意义的新方法,以优先考虑生物变量. 这种方法可以更好地识别1型糖尿病研究的关键遗传关联.

关键词:
在GWAS中,GWAS就是GWAS.效果大小效果大小的影响经验上的贝叶斯贝叶斯.错误发现率 错误发现率意义上的意义意义的意义.

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